Norgestimate inhibits staphylococcal biofilm formation and resensitizes methicillin-resistant Staphylococcus aureus to β-lactam antibiotics

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Yoshii, Yutaka ; Okuda, Ken-ichi ; Yamada, Satomi ; Nagakura, Mari ; Sugimoto, Shinya ; Nagano, Tetsuo ; Okabe, Takayoshi ; Kojima, Hirotatsu ; Iwamoto, Takeo ; Kuwano, Kazuyoshi ; Mizunoe, Yoshimitsu (2017)
  • Publisher: Nature Publishing Group UK
  • Journal: NPJ Biofilms and Microbiomes, volume 3 (eissn: 2055-5008)
  • Related identifiers: doi: 10.1038/s41522-017-0026-1, pmc: PMC5522392
  • Subject: Article
    mesheuropmc: biochemical phenomena, metabolism, and nutrition

Formation of bacterial biofilms on medical devices can cause severe or fatal infectious diseases. In particular, biofilm-associated infections caused by methicillin-resistant Staphylococcus aureus are difficult to eradicate because the biofilm is strongly resistant to a... View more
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