Norgestimate inhibits staphylococcal biofilm formation and resensitizes methicillin-resistant Staphylococcus aureus to β-lactam antibiotics

Article English OPEN
Yoshii, Yutaka; Okuda, Ken-ichi; Yamada, Satomi; Nagakura, Mari; Sugimoto, Shinya; Nagano, Tetsuo; Okabe, Takayoshi; Kojima, Hirotatsu; Iwamoto, Takeo; Kuwano, Kazuyoshi; Mizunoe, Yoshimitsu;
  • Publisher: Nature Publishing Group UK
  • Journal: NPJ Biofilms and Microbiomes,volume 3 (eissn: 2055-5008)
  • Related identifiers: doi: 10.1038/s41522-017-0026-1, pmc: PMC5522392
  • Subject: Article
    mesheuropmc: biochemical phenomena, metabolism, and nutrition

Formation of bacterial biofilms on medical devices can cause severe or fatal infectious diseases. In particular, biofilm-associated infections caused by methicillin-resistant Staphylococcus aureus are difficult to eradicate because the biofilm is strongly resistant to a... View more
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