The Ubiquitin Ligase Hul5 Promotes Proteasomal Processivity▿

Other literature type English OPEN
Aviram, Sharon; Kornitzer, Daniel;

The 26S proteasome is a large cytoplasmic protease that degrades polyubiquitinated proteins to short peptides in a processive manner. The proteasome 19S regulatory subcomplex tethers the target protein via its polyubiquitin adduct and unfolds the target polypeptide, whi... View more
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