Neuropeptide S Counteracts Paradoxical Sleep Deprivation-Induced Anxiety-Like Behavior and Sleep Disturbances

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Xie, Jun-Fan; Shao, Yu-Feng; Wang, Hai-Liang; Wang, Can; Cui, Guang-Fu; Kong, Xiang-Pan; Wang, Lin-Xin; Chen, Yu-Nong; Cong, Chao-Yu; Chen, Hai-Lin; Hou, Yi-Ping;
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Cellular Neuroscience, volume 12 ( eissn: 1662-5102)
  • Publisher copyright policies & self-archiving
  • Identifiers: pmc: PMC5845547, doi: 10.3389/fncel.2018.00064
  • Subject: neuropeptide S | amygdala | Neuroscience | sleep-wake states | Original Research | anxiety-like behavior | neuropeptide S receptor | paradoxical sleep deprivation
    mesheuropmc: nervous system | psychological phenomena and processes | mental disorders

Disturbed sleep is a common subjective complaint among individuals with anxiety disorders. Sleep deprivation increases general and specific anxiety symptoms among healthy individuals. The amygdala is critical for regulating anxiety and also involved in mediating the eff... View more
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