KDM4C, a H3K9me3 Histone Demethylase, is Involved in the Maintenance of Human ESCC-Initiating Cells by Epigenetically Enhancing SOX2 Expression1

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Yuan, Xiang; Kong, Jinyu; Ma, Zhikun; Li, Na; Jia, Ruinuo; Liu, Yiwen; Zhou, Fuyou; Zhan, Qimin; Liu, Gang; Gao, Shegan;

Our studies investigating the existence of tumor-initiating cell (TIC) populations in human esophageal squamous cell carcinoma (ESCC) had identified a subpopulation of cells isolated from ESCC patient-derived tumor specimens marked by an ALDHbri+ phenotype bear stem cel... View more
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