Interest of integrins targeting in glioblastoma according to tumor heterogeneity and cancer stem cell paradigm: an update

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Malric, Laure; Monferran, Sylvie; Gilhodes, Julia; Boyrie, Sabrina; Dahan, Perrine; Skuli, Nicolas; Sesen, Julie; Filleron, Thomas; Kowalski-Chauvel, Aline; Cohen-Jonathan Moyal, Elizabeth; Toulas, Christine; Lemarié, Anthony;

Glioblastomas are malignant brain tumors with dismal prognosis despite standard treatment with surgery and radio/chemotherapy. These tumors are defined by an important cellular heterogeneity and notably contain a particular subpopulation of Glioblastoma-initiating cells... View more
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