Hul5 ubiquitin ligase: Good riddance to bad proteins

Other literature type English OPEN
Fang, Nancy N.; Mayor, Thibault;
(2012)

Failure to eliminate abnormal proteins in the cell is associated with numerous aggregation diseases. Misfolded proteins are normally detected by protein quality control and either refolded or eliminated. The ubiquitin-proteasome system is a major pathway that degrades t... View more
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