Glioblastoma multiforme-derived extracellular vesicles drive normal astrocytes towards a tumour-enhancing phenotype

Other literature type English OPEN
Oushy, Soliman; Hellwinkel, Justin E.; Wang, Mary; Nguyen, Ger J.; Gunaydin, Dicle; Harland, Tessa A.; Anchordoquy, Thomas J.; Graner, Michael W.;

Glioblastoma multiforme (GBM) is a devastating tumour with abysmal prognoses. We desperately need novel approaches to understand GBM biology and therapeutic vulnerabilities. Extracellular vesicles (EVs) are membrane-enclosed nanospheres released locally and systemically... View more
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