Daclizumab reverses intrathecal immune cell abnormalities in multiple sclerosis

Article English OPEN
Lin, Yen Chih; Winokur, Paige; Blake, Andrew; Wu, Tianxia; Romm, Elena; Bielekova, Bibiana;
(2015)
  • Publisher: BlackWell Publishing Ltd
  • Journal: Annals of Clinical and Translational Neurology,volume 2,issue 5,pages445-455 (issn: 2328-9503, eissn: 2328-9503)
  • Related identifiers: doi: 10.1002/acn3.181, pmc: PMC4435700
  • Subject: Research Articles

Objective Novel treatments such as natalizumab and fingolimod achieve their therapeutic efficacy in multiple sclerosis (MS) by blocking access of subsets of immune cells into the central nervous system, thus creating nonphysiological intrathecal immunity. In contrast, d... View more
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