publication . Article . 2014

Evaluation of interleukin-1β and 8 in gutka chewers with periodontitis among a rural Indian population

Pulikkotil Shaju Jacob; Sonia Nath; Ritu Prabha Patel;
Open Access English
  • Published: 01 Jun 2014 Journal: Journal of Periodontal & Implant Science, volume 44, issue 3, pages 126-133 (issn: 2093-2278, eissn: 2093-2286, Copyright policy)
  • Publisher: Korean Academy of Periodontology
Abstract
Purpose: Smokeless tobacco-based oral-use products like gutka are popular in India. Gutka usage leads to increased periodontal destruction and inflammation; however, the relevant mechanism remains unknown. This study aimed to elucidate the role of gutka in periodontitis by examining its effect on the levels of interleukin (IL) 1β and IL-8 from the gingival crevicular fluid (GCF). Methods: A total of 45 patients were enrolled in this study. Thirty patients with periodontitis (15 gutka chewers [GCP] and 15 nongutka chewers [NGC]) and 15 periodontally healthy controls (HC) were selected. The full-mouth plaque index (PI), gingival index (GI), probing depth (PD), cli...
Subjects
free text keywords: Research Article, Cytokine, Interleukin-1beta, Interleukin-8, Periodontitis, Smokeless tobacco, Oral Surgery, Periodontics, Crevicular fluid, Positive correlation, Surgery, medicine.medical_specialty, medicine, Dentistry, business.industry, business, Interleukin, Population, education.field_of_study, education, Gutka, medicine.disease
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publication . Article . 2014

Evaluation of interleukin-1β and 8 in gutka chewers with periodontitis among a rural Indian population

Pulikkotil Shaju Jacob; Sonia Nath; Ritu Prabha Patel;