Tetracycline-Inducible Expression of Individual Secreted Aspartic Proteases in Candida albicans Allows Isoenzyme-Specific Inhibitor Screening▿

Other literature type English OPEN
Staib, Peter; Lermann, Ulrich; Blaβ-Warmuth, Julia; Degel, Björn; Würzner, Reinhard; Monod, Michel; Schirmeister, Tanja; Morschhäuser, Joachim;

The yeast Candida albicans possesses a gene family that encodes secreted aspartic proteases (Saps), which are important for the virulence of this human fungal pathogen. Inhibitors of the Saps could therefore be used as novel antimycotic agents for the treatment of C. al... View more
Share - Bookmark