Outcome after neoadjuvant chemotherapy in elderly breast cancer patients – a pooled analysis of individual patient data from eight prospectively randomized controlled trials

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von Waldenfels, Gabriel; Loibl, Sibylle; Furlanetto, Jenny; Machleidt, Anna; Lederer, Bianca; Denkert, Carsten; Hanusch, Claus; Kümmel, Sherko; von Minckwitz, Gunter; Schneeweiss, Andreas; Untch, Michael; Rhiem, Kerstin; Fasching, Peter A.; Blohmer, Jens-Uwe;
  • Publisher: Impact Journals LLC
  • Journal: Oncotarget,volume 9,issue 20,pages15,168-15,179 (eissn: 1949-2553)
  • Related identifiers: pmc: PMC5880594, doi: 10.18632/oncotarget.24586
  • Subject: neoadjuvant | elderly | cancer survival | Gerotarget | Research Paper: Gerotarget (Focus on Aging) | breast | pCR

Introduction Recent studies showed the high and independent impact of age (<40 years) on pathologic complete response (pCR) and prognosis for patients undergoing neoadjuvant chemotherapy (NACT). Some physicians might not consider elderly patients (>65 years) for NACT du... View more
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