publication . Other literature type . 2003

Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies.

Falush, Daniel; Stephens, Matthew; Pritchard, Jonathan K;
Open Access English
  • Published: 01 Aug 2003
Abstract
We describe extensions to the method of Pritchard et al. for inferring population structure from multilocus genotype data. Most importantly, we develop methods that allow for linkage between loci. The new model accounts for the correlations between linked loci that arise in admixed populations ("admixture linkage disequilibium"). This modification has several advantages, allowing (1) detection of admixture events farther back into the past, (2) inference of the population of origin of chromosomal regions, and (3) more accurate estimates of statistical uncertainty when linked loci are used. It is also of potential use for admixture mapping. In addition, we descri...
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pmc: PMC1462648
pmid: 12930761
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free text keywords: Research Article
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Other literature type . 2003
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