Older fathers' children have lower evolutionary fitness across four centuries and in four populations

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Arslan, Ruben C.; Willführ, Kai P.; Frans, Emma M.; Verweij, Karin J. H.; Bürkner, Paul-Christian; Myrskylä, Mikko; Voland, Eckart; Almqvist, Catarina; Zietsch, Brendan P.; Penke, Lars;
(2017)
  • Publisher: Royal Society of London
  • Journal: Proceedings of the Royal Society B: Biological Sciences, volume 284, issue 1,862 (issn: 0962-8452, eissn: 1471-2954)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC5597845, doi: 10.1098/rspb.2017.1562
  • Subject: Agricultural and Biological Sciences(all) | Research Article | Immunology and Microbiology(all) | QH301 Biology | paternal age | Evolution | evolutionary fitness | QH426 Genetics | 197 | mutation | Environmental Science(all) | Biochemistry, Genetics and Molecular Biology(all) | genetic load | 5141 Sociology | 1001 | 70 | reproductive success

Higher paternal age at offspring conception increases de novo genetic mutations. Based on evolutionary genetic theory we predicted older fathers' children, all else equal, would be less likely to survive and reproduce, i.e. have lower fitness. In sibling control studies... View more
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