publication . Other literature type . Article . 2018

3D Fabrication with Integration Molding of a Graphene Oxide/Polycaprolactone Nanoscaffold for Neurite Regeneration and Angiogenesis.

Qian, Yun; Song, Jialin; Zhao, Xiaotian; Chen, Wei; Ouyang, Yuanming; Yuan, Weien; Fan, Cunyi;
  • Published: 26 Jan 2018
  • Publisher: Wiley
Abstract
Abstract Treating peripheral nerve injury faces major challenges and may benefit from bioactive scaffolds due to the limited autograft resources. Graphene oxide (GO) has emerged as a promising nanomaterial with excellent physical and chemical properties. GO has functional groups that confer biocompatibility that is better than that of graphene. Here, GO/polycaprolactone (PCL) nanoscaffolds are fabricated using an integration molding method. The nanoscaffolds exhibit many merits, including even GO nanoparticle distribution, macroporous structure, and strong mechanical support. Additionally, the process enables excellent quality control. In vitro studies confirm t...
Subjects
free text keywords: General Engineering, General Physics and Astronomy, General Materials Science, Medicine (miscellaneous), General Chemical Engineering, Biochemistry, Genetics and Molecular Biology (miscellaneous), Biocompatibility, Tissue engineering, In vivo, Nerve guidance conduit, Schwann cell proliferation, Biomedical engineering, Nanotechnology, Materials science, Polycaprolactone, chemistry.chemical_compound, chemistry, Angiogenesis, Peripheral nerve injury, Full Paper, Full Papers, graphene oxide, nerve conduits, peripheral nerve injuries, signaling pathways, vascular endothelial growth factor
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publication . Other literature type . Article . 2018

3D Fabrication with Integration Molding of a Graphene Oxide/Polycaprolactone Nanoscaffold for Neurite Regeneration and Angiogenesis.

Qian, Yun; Song, Jialin; Zhao, Xiaotian; Chen, Wei; Ouyang, Yuanming; Yuan, Weien; Fan, Cunyi;