Association Between APOL1 Genotypes and Risk of Cardiovascular Disease in MESA (Multi‐Ethnic Study of Atherosclerosis)

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Chen, Teresa K.; Katz, Ronit; Estrella, Michelle M.; Gutierrez, Orlando M.; Kramer, Holly; Post, Wendy S.; Shlipak, Michael G.; Wassel, Christina L.; Peralta, Carmen A.;
  • Publisher: John Wiley and Sons Inc.
  • Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease,volume 6,issue 12 (eissn: 2047-9980)
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  • Related identifiers: doi: 10.1161/JAHA.117.007199, pmc: PMC5779033
  • Subject: Coronary Artery Disease | Epidemiology | Cardiovascular Disease | Heart Failure | coronary artery calcium | Genetics | Multi‐Ethnic Study of Atherosclerosis | Cerebrovascular Disease/Stroke | Original Research | APOL1

Background APOL1 genetic variants confer an increased risk for kidney disease. Their associations with cardiovascular disease (CVD) are less certain. We aimed to compare the prevalence of subclinical CVD and incidence of atherosclerotic CVD and heart failure by APOL1 ge... View more