publication . Article . Preprint . Other literature type . 2018

The Drosophila microbiome has a limited influence on sleep, activity, and courtship behaviors

Joel Selkrig; Farhan Mohammad; Soon Hwee Ng; Chua Jia Yi; Tayfun Tumkaya; Joses Ho; Yin Ning Chiang; Dirk Rieger; Sven Pettersson; Charlotte Helfrich-Förster; ...
  • Published: 13 Jul 2018
Abstract
<jats:title>Abstract</jats:title><jats:p>In animals, commensal microbes modulate various physiological functions, including behavior. While microbiota exposure is required for normal behavior in mammals, it is not known how widely this dependency is present in other animal species. We proposed the hypothesis that the microbiome has a major influence on the behavior of the vinegar fly (<jats:italic>Drosophila melanogaster</jats:italic>), a major invertebrate model organism. Several assays were used to test the contribution of the microbiome on some well-characterized behaviors: defensive behavior, sleep, locomotion, and courtship in microbe-bearing, control flies...
Subjects
free text keywords: Medicine, R, Science, Q, Article, Multidisciplinary, Microbiome, Model organism, ved/biology.organism_classification_rank.species, ved/biology, Animal species, Evolutionary biology, Biology, Drosophila melanogaster, biology.organism_classification, Courtship, media_common.quotation_subject, media_common, Genetics
60 references, page 1 of 4

Rooks, MG, Garrett, WS. Gut microbiota, metabolites and host immunity. Nat. Rev. Immunol.. 2016; 16: 341-352 [OpenAIRE] [PubMed] [DOI]

Arrieta, M-C. Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci. Transl. Med.. 2015; 7: 307ra152 [OpenAIRE] [PubMed] [DOI]

Russell, SL. Perinatal antibiotic-induced shifts in gut microbiota have differential effects on inflammatory lung diseases. J. Allergy Clin. Immunol.. 2015; 135: 100-109 [OpenAIRE] [PubMed] [DOI]

Sonnenburg, JL, Bäckhed, F. Diet-microbiota interactions as moderators of human metabolism. Nature. 2016; 535: 56-64 [OpenAIRE] [PubMed] [DOI]

Hsiao, EY. Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell. 2013; 155: 1451-1463 [OpenAIRE] [PubMed] [DOI]

Stilling, RM, Bordenstein, SR, Dinan, TG, Cryan, JF. Friends with social benefits: host-microbe interactions as a driver of brain evolution and development?. Front. Cell. Infect. Microbiol.. 2014; 4: 147 [OpenAIRE] [PubMed] [DOI]

Sampson, TR, Mazmanian, SK. Control of brain development, function, and behavior by the microbiome. Cell Host Microbe. 2015; 17: 565-576 [OpenAIRE] [PubMed] [DOI]

Selkrig, J, Wong, P, Zhang, X, Pettersson, S. Metabolic tinkering by the gut microbiome: Implications for brain development and function. Gut Microbes. 2014; 5: 369-380 [OpenAIRE] [PubMed] [DOI]

Sharon, G, Sampson, TR, Geschwind, DH, Mazmanian, SK. The Central Nervous System and the Gut Microbiome. Cell. 2016; 167: 915-932 [OpenAIRE] [PubMed] [DOI]

Fung, TC, Olson, CA, Hsiao, EY. Interactions between the microbiota, immune and nervous systems in health and disease. Nat. Neurosci.. 2017; 20: 145-155 [OpenAIRE] [PubMed] [DOI]

Goyal, MS, Venkatesh, S, Milbrandt, J, Gordon, JI, Raichle, ME. Feeding the brain and nurturing the mind: Linking nutrition and the gut microbiota to brain development. Proc. Natl. Acad. Sci. USA. 2015; 112: 14105-14112 [OpenAIRE] [PubMed] [DOI]

12.Foster, J. A. & McVey Neufeld, K.-A. Gut–brain axis: how the microbiome influences anxiety and depression. Trends Neurosci. 36, 305–312 (2013/5).

Ogbonnaya, ES. Adult Hippocampal Neurogenesis Is Regulated by the Microbiome. Biol. Psychiatry. 2015; 78: e7-9 [OpenAIRE] [PubMed] [DOI]

Borre, YE. Microbiota and neurodevelopmental windows: implications for brain disorders. Trends Mol. Med.. 2014; 20: 509-518 [OpenAIRE] [PubMed] [DOI]

Clarke, G. The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Mol. Psychiatry. 2013; 18: 666-673 [OpenAIRE] [PubMed] [DOI]

60 references, page 1 of 4
Abstract
<jats:title>Abstract</jats:title><jats:p>In animals, commensal microbes modulate various physiological functions, including behavior. While microbiota exposure is required for normal behavior in mammals, it is not known how widely this dependency is present in other animal species. We proposed the hypothesis that the microbiome has a major influence on the behavior of the vinegar fly (<jats:italic>Drosophila melanogaster</jats:italic>), a major invertebrate model organism. Several assays were used to test the contribution of the microbiome on some well-characterized behaviors: defensive behavior, sleep, locomotion, and courtship in microbe-bearing, control flies...
Subjects
free text keywords: Medicine, R, Science, Q, Article, Multidisciplinary, Microbiome, Model organism, ved/biology.organism_classification_rank.species, ved/biology, Animal species, Evolutionary biology, Biology, Drosophila melanogaster, biology.organism_classification, Courtship, media_common.quotation_subject, media_common, Genetics
60 references, page 1 of 4

Rooks, MG, Garrett, WS. Gut microbiota, metabolites and host immunity. Nat. Rev. Immunol.. 2016; 16: 341-352 [OpenAIRE] [PubMed] [DOI]

Arrieta, M-C. Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci. Transl. Med.. 2015; 7: 307ra152 [OpenAIRE] [PubMed] [DOI]

Russell, SL. Perinatal antibiotic-induced shifts in gut microbiota have differential effects on inflammatory lung diseases. J. Allergy Clin. Immunol.. 2015; 135: 100-109 [OpenAIRE] [PubMed] [DOI]

Sonnenburg, JL, Bäckhed, F. Diet-microbiota interactions as moderators of human metabolism. Nature. 2016; 535: 56-64 [OpenAIRE] [PubMed] [DOI]

Hsiao, EY. Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell. 2013; 155: 1451-1463 [OpenAIRE] [PubMed] [DOI]

Stilling, RM, Bordenstein, SR, Dinan, TG, Cryan, JF. Friends with social benefits: host-microbe interactions as a driver of brain evolution and development?. Front. Cell. Infect. Microbiol.. 2014; 4: 147 [OpenAIRE] [PubMed] [DOI]

Sampson, TR, Mazmanian, SK. Control of brain development, function, and behavior by the microbiome. Cell Host Microbe. 2015; 17: 565-576 [OpenAIRE] [PubMed] [DOI]

Selkrig, J, Wong, P, Zhang, X, Pettersson, S. Metabolic tinkering by the gut microbiome: Implications for brain development and function. Gut Microbes. 2014; 5: 369-380 [OpenAIRE] [PubMed] [DOI]

Sharon, G, Sampson, TR, Geschwind, DH, Mazmanian, SK. The Central Nervous System and the Gut Microbiome. Cell. 2016; 167: 915-932 [OpenAIRE] [PubMed] [DOI]

Fung, TC, Olson, CA, Hsiao, EY. Interactions between the microbiota, immune and nervous systems in health and disease. Nat. Neurosci.. 2017; 20: 145-155 [OpenAIRE] [PubMed] [DOI]

Goyal, MS, Venkatesh, S, Milbrandt, J, Gordon, JI, Raichle, ME. Feeding the brain and nurturing the mind: Linking nutrition and the gut microbiota to brain development. Proc. Natl. Acad. Sci. USA. 2015; 112: 14105-14112 [OpenAIRE] [PubMed] [DOI]

12.Foster, J. A. & McVey Neufeld, K.-A. Gut–brain axis: how the microbiome influences anxiety and depression. Trends Neurosci. 36, 305–312 (2013/5).

Ogbonnaya, ES. Adult Hippocampal Neurogenesis Is Regulated by the Microbiome. Biol. Psychiatry. 2015; 78: e7-9 [OpenAIRE] [PubMed] [DOI]

Borre, YE. Microbiota and neurodevelopmental windows: implications for brain disorders. Trends Mol. Med.. 2014; 20: 509-518 [OpenAIRE] [PubMed] [DOI]

Clarke, G. The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Mol. Psychiatry. 2013; 18: 666-673 [OpenAIRE] [PubMed] [DOI]

60 references, page 1 of 4
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publication . Article . Preprint . Other literature type . 2018

The Drosophila microbiome has a limited influence on sleep, activity, and courtship behaviors

Joel Selkrig; Farhan Mohammad; Soon Hwee Ng; Chua Jia Yi; Tayfun Tumkaya; Joses Ho; Yin Ning Chiang; Dirk Rieger; Sven Pettersson; Charlotte Helfrich-Förster; ...