publication . Other literature type . Article . 2013

Comparative Evaluation of Serotonin Toxicity among Veterans Affairs Patients Receiving Linezolid and Vancomycin

T. P. Lodise; N. Patel; A. Rivera; L. Tristani; V. Lazariu; H. Vandewall; L. A. McNutt;
Open Access English
  • Published: 16 Sep 2013
  • Publisher: American Society for Microbiology
Abstract
<jats:title>ABSTRACT</jats:title><jats:p>Despite the theoretical risk of serotonin toxicity (ST) with linezolid, “real-world” clinical evaluations of the risk of ST in patients receiving linezolid have been limited to case reports and noncomparator studies. An observational, matched-cohort study was conducted to evaluate the risk of ST among hospitalized patients who received linezolid or vancomycin at the Upstate New York Veterans Affairs Healthcare Network (Veterans Integrated Service Network 2 [VISN-2]). Matching criteria included VISN-2 hospital, hospital ward, prior hospital length of stay, age, and baseline platelet counts. The patients' electronic medical...
Subjects
free text keywords: Clinical Therapeutics, Pharmacology (medical), Pharmacology, Infectious Diseases, Population study, Word search, Linezolid, chemistry.chemical_compound, chemistry, Internal medicine, medicine.medical_specialty, medicine, Veterans Affairs, Virology, Adverse effect, Intensive care medicine, business.industry, business, Antidepressant, Vancomycin, medicine.drug, Cohort study
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