Endothelial lipid phosphate phosphatase-3 deficiency that disrupts the endothelial barrier function is a modifier of cardiovascular development

Article English OPEN
Chatterjee, Ishita ; Baruah, Jugajyoti ; Lurie, Erin E. ; Wary, Kishore K. (2016)
  • Publisher: Oxford University Press
  • Journal: Cardiovascular Research, volume 111, issue 1, pages 105-118 (issn: 0008-6363, eissn: 1755-3245)
  • Related identifiers: pmc: PMC4909162, doi: 10.1093/cvr/cvw090
  • Subject: Beta-catenin | LPP3 | ORIGINAL ARTICLES | Neovascularization | VE-cadherin | PPAP2b | Vascular Biology
    mesheuropmc: embryonic structures

Aims Lipid phosphate phosphatase-3 (LPP3) is expressed at high levels in endothelial cells (ECs). Although LPP3 is known to hydrolyse the phosphate group from lysolipids such as spingosine-1-phosphate and its structural homologues, the function of Lpp3 in ECs is not com... View more
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