Nanos2 suppresses meiosis and promotes male germ cell differentiation

Other literature type English OPEN
Suzuki, Atsushi; Saga, Yumiko;

In mouse fetal gonads, retinoic acid (RA) induces meiosis in the female germ cells, whereas the male germ cells never enter meiosis due to Cyp26b1-mediated RA metabolism. We show here that Nanos2 plays critical roles in the differentiation of male germ cells. We find th... View more
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