Exploration of α1-Antitrypsin Treatment Protocol for Islet Transplantation: Dosing Plan and Route of Administration
Baranovski, Boris M.
Ochayon, David E.
Mizrahi, Mark I.
Lewis, Eli C.
- Publisher: The American Society for Pharmacology and Experimental Therapeutics
The Journal of Pharmacology and Experimental Therapeutics,
(issn: 0022-3565, eissn: 1521-0103)
Inflammation, Immunopharmacology, and Asthma
Lifelong weekly infusions of human α1-antitrypsin (hAAT) are currently administered as augmentation therapy for patients with genetic AAT deficiency (AATD). Several recent clinical trials attempt to extend hAAT therapy to conditions outside AATD, including type 1 diabet...