publication . Article . 2016

Pathomorphological features of calcinosis circumscripta in a dog

Lee, Eun-Mi; Kim, Ah-Young; Lee, Eun-Joo; Jeong, Kyu-Shik;
Open Access English
  • Published: 01 Dec 2016 Journal: Laboratory Animal Research (issn: 2233-7660, Copyright policy)
  • Publisher: BMC
Abstract
Abstract A 19-month-old male German shepherd dog was presented with a hindlimb footpad mass. The mass was excised and histopathology was performed. Grossly, the cut section of the mass had multiple wellcircumscribed nodules with a chalky appearance. Histopathologically, basophilic-stained calcium deposits of various sizes were distributed from dermis to subcutis, surrounded by epithelioid cells, multinucleated giant cells, and reactive fibroblasts. Myxoid metaplasia, calcium deposits in hair follicles, and psammomalike bodies were also found. These histopathologic observations will greatly help to understand the pathogenesis of calcinosis circumscripta.
Subjects
free text keywords: Calcinosis circumscripta, histopathologic diagnosis, myxoid change, Psammoma-like body, Medicine (General), R5-920, Biology (General), QH301-705.5, Case Report, Metaplasia, medicine.symptom, medicine, Histopathology, medicine.medical_specialty, Calcium, chemistry.chemical_element, chemistry, German Shepherd Dog, Anatomy, Dermis, medicine.anatomical_structure, Pathology, Epithelioid cell, Giant cell, Hindlimb, Biology
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publication . Article . 2016

Pathomorphological features of calcinosis circumscripta in a dog

Lee, Eun-Mi; Kim, Ah-Young; Lee, Eun-Joo; Jeong, Kyu-Shik;