An Engineered Metal Sensor Tunes the Kinetics of Synaptic Transmission

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Evans, Chantell S.; Ruhl, David A.; Chapman, Edwin R.;

The Ca2+ sensor synaptotagmin-1 (syt-1) regulates neurotransmitter release by interacting with anionic phospholipids. Here we test the idea that the intrinsic kinetics of syt–membrane interactions determine, in part, the time course of synaptic transmission. To tune the... View more
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