publication . Article . Other literature type . 2007

EFFECTS OF SPECIFIC DOSAGES OF MAGNESIUM AND ZINC ON THE TERATOGENICITY OF CADMIUM, NICKEL, AND COBALT IN XENOPUS EMBRYOS, AS ASSESSED BY THE FETAX TEST

Boga, Ayper; Erdogan, Seref; Sertdemir, Yasar;
Open Access English
  • Published: 22 Jan 2007
  • Country: Turkey
Abstract
The objective of this study was to determine if exposure to divalent cations, Cd2+, Ni2+, and Co2+ would lead to malformations in Xenopus laevis embryos, and whether addition of Mg 2+and Zn2+; separately and in combination, would reduce their toxicity and teratogenicity on the embryos of Xenopus laevis as assessed by 96-h FETAX tests. Results indicate that exposure to Cd2+, Ni 2+ or Co2+ lead to an increase in toxicity and teratogenicity in embryos, whereas Mg2+, Zn2+, or a combination of them reduced the toxic and terato- genic effects of these divalent cations. Modulation of Cd2+, Ni2+ or Co 2+ toxicity and ter- atogenicity by Mg2+ and Zn 2+, varied with the m...
Subjects
Medical Subject Headings: inorganic chemicalsembryonic structuresanimal structures
free text keywords: FETAX, Magnesium (Mg2+), Metal Interaction, Xenopus, Zinc (Zn 2+)), Therapeutics. Pharmacology, RM1-950, Articles, Metal, visual_art.visual_art_medium, visual_art, Embryo, biology.organism_classification, biology, Divalent, chemistry.chemical_classification, chemistry, Magnesium, chemistry.chemical_element, Cadmium, Toxicology, Zinc, Toxicity
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publication . Article . Other literature type . 2007

EFFECTS OF SPECIFIC DOSAGES OF MAGNESIUM AND ZINC ON THE TERATOGENICITY OF CADMIUM, NICKEL, AND COBALT IN XENOPUS EMBRYOS, AS ASSESSED BY THE FETAX TEST

Boga, Ayper; Erdogan, Seref; Sertdemir, Yasar;