Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells

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Matsumoto, Akihiro ; Takahashi, Yuki ; Nishikawa, Makiya ; Sano, Kohei ; Morishita, Masaki ; Charoenviriyakul, Chonlada ; Saji, Hideo ; Takakura, Yoshinobu (2017)
  • Publisher: John Wiley and Sons Inc.
  • Journal: Cancer Science, volume 108, issue 9, pages 1,803-1,810 (issn: 1347-9032, eissn: 1349-7006)
  • Related identifiers: doi: 10.1111/cas.13310, pmc: PMC5581513
  • Subject: Original Article | Biodistribution | proliferation | uptake | exosomes | Original Articles | Cell, Molecular, and Stem Cell Biology | melanoma

Exosomes are extracellular vesicles released by various cell types and play roles in cell–cell communication. Several studies indicate that cancer cell‐derived exosomes play important pathophysiological roles in tumor progression. Biodistribution of cancer cell‐derived ... View more
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