Identification of type IV collagen exposure as a molecular imaging target for early detection of thoracic aortic dissection

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Xu, Ke ; Xu, Chen ; Zhang, Yanzhenzi ; Qi, Feiran ; Yu, Bingran ; Li, Ping ; Jia, Lixin ; Li, Yulin ; Xu, Fu-jian ; Du, Jie (2018)
  • Publisher: Ivyspring International Publisher
  • Journal: Theranostics, volume 8, issue 2, pages 437-449 (eissn: 1838-7640)
  • Related identifiers: pmc: PMC5743559, doi: 10.7150/thno.22467
  • Subject: Thoracic aortic dissection | Early diagnosis | Magnetic resonance imaging | Risk prediction | Fluorescence imaging. | Research Paper

Thoracic aortic dissection (TAD) is an aggressive and life-threatening vascular disease and there is no effective means of early diagnosis of dissection. Type IV collagen (Col-IV) is a major component of the sub-endothelial basement membrane, which is initially exposed ... View more
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