The Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Inhibits Expression of SUMO/Sentrin-Specific Peptidase 6 To Facilitate Establishment of Latency

Other literature type English OPEN
Lin, Xiaoxi ; Sun, Rui ; Zhang, Fang ; Gao, Yuan ; Bin, Lianghua ; Lan, Ke (2017)
  • Publisher: American Society for Microbiology
  • Related identifiers: pmc: PMC5553180, doi: 10.1128/JVI.00806-17
  • Subject: Virus-Cell Interactions
    mesheuropmc: biochemical phenomena, metabolism, and nutrition | viruses | virus diseases

Kaposi's sarcoma-associated herpesvirus (KSHV), which belongs to the Gammaherpesviridae, typically displays two different phases in its life cycle, the latent phase and the lytic phase. Latency-associated nuclear antigen (LANA), the primary viral product during latency,... View more
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