Effect of diethyldithiocarbamate rescue on tumor response to cis-platinum in a rat model.

Other literature type English OPEN
Borch, R F; Katz, J C; Lieder, P H; Pleasants, M E;
  • Related identifiers: pmc: PMC350075
  • Subject: Research Article
    mesheuropmc: endocrine system diseases

The nephrotoxic effects of cis-dichlorodiamineplatinum(II) (NSC-119875) (DDP) in female F344 rats were effectively inhibited by administration of sodium diethyldithiocarbamate (DDTC) in doses of 750 mg/kg intraperitoneally or 100 mg/kg intravenously 2 hr after administr... View more
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