publication . Article . Other literature type . 2017

Reductions in prostatic doses are associated with less acute morbidity in patients undergoing Pd-103 brachytherapy: Substantiation of the rationale for focal therapy

Ferro, Adam; Bae, Hee Joon; Yenokyan, Gayane; Le, Yi; McNutt, Todd; Mian, Omar; Gergis, Carol; Haviland, Chloe; DeWeese, Theodore L.; Song, Daniel Y.;
Open Access
  • Published: 23 Nov 2017 Journal: Brachytherapy, volume 17, pages 313-318 (issn: 1538-4721, Copyright policy)
  • Publisher: Elsevier BV
Abstract
Abstract Purpose Interest in prostate dose reduction or focal treatment exists due to expected reductions in treatment morbidity. Prior analyses have not generally corroborated relationships between prostate or urethral dose and urinary toxicity after brachytherapy, but such analyses have been performed on cohorts all receiving the same prescribed dose. We analyzed patients treated to differing prescription doses to assess acute urinary morbidity with dose reduction. Methods and Materials Patients treated with Pd-103 to either 125 Gy or 90–100 Gy were compared using the International Prostate Symptom Score (IPSS) at 1-month postimplant. Patients in the 90–100 Gy...
Subjects
free text keywords: Oncology, Radiology Nuclear Medicine and imaging, Brachytherapy, medicine.medical_treatment, medicine, Prostate, medicine.anatomical_structure, Toxicity, Radiology, medicine.medical_specialty, Radiation therapy, International Prostate Symptom Score, Urinary system, Cohort, Dosimetry, business.industry, business, Article
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publication . Article . Other literature type . 2017

Reductions in prostatic doses are associated with less acute morbidity in patients undergoing Pd-103 brachytherapy: Substantiation of the rationale for focal therapy

Ferro, Adam; Bae, Hee Joon; Yenokyan, Gayane; Le, Yi; McNutt, Todd; Mian, Omar; Gergis, Carol; Haviland, Chloe; DeWeese, Theodore L.; Song, Daniel Y.;