Imaging viscosity of intragranular mucin matrix in cystic fibrosis cells

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Requena, Sebastian; Ponomarchuk, Olga; Castillo, Marlius; Rebik, Jonathan; Brochiero, Emmanuelle; Borejdo, Julian; Gryczynski, Ignacy; Dzyuba, Sergei V.; Gryczynski, Zygmunt; Grygorczyk, Ryszard; Fudala, Rafal;

Abstract Abnormalities of mucus viscosity play a critical role in the pathogenesis of several respiratory diseases, including cystic fibrosis. Currently, there are no approaches to assess the rheological properties of mucin granule matrices in live cells. This is the fi... View more
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