Non-coding RNAs derived from an alternatively spliced REST transcript (REST-003) regulate breast cancer invasiveness

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Sook Lee, Nan; Evgrafov, Oleg V.; Souaiaia, Tade; Bonyad, Adrineh; Herstein, Jennifer; Yeun Lee, Joo; Kim, Jihong; Ning, Yan; Sixto, Marcos; Weitz, Andrew C.; Lenz, Heinz-Josef; Wang, Kai; Knowles, James A.; Press, Michael F.; Salvaterra, Paul M.; Kirk Shung, K.; Chow, Robert H.;
(2015)

RE1-Silencing Transcription factor (REST) has a well-established role in regulating transcription of genes important for neuronal development. Its role in cancer, though significant, is less well understood. We show that REST downregulation in weakly invasive MCF-7 brea... View more
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