Non-coding RNAs derived from an alternatively spliced REST transcript (REST-003) regulate breast cancer invasiveness

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Sook Lee, Nan ; Evgrafov, Oleg V. ; Souaiaia, Tade ; Bonyad, Adrineh ; Herstein, Jennifer ; Yeun Lee, Joo ; Kim, Jihong ; Ning, Yan ; Sixto, Marcos ; Weitz, Andrew C. ; Lenz, Heinz-Josef ; Wang, Kai ; Knowles, James A. ; Press, Michael F. ; Salvaterra, Paul M. ; Kirk Shung, K. ; Chow, Robert H. (2015)

RE1-Silencing Transcription factor (REST) has a well-established role in regulating transcription of genes important for neuronal development. Its role in cancer, though significant, is less well understood. We show that REST downregulation in weakly invasive MCF-7 brea... View more
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