edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens

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Dai, Zhiyin; Sheridan, Julie M.; Gearing, Linden J.; Moore, Darcy L.; Su, Shian; Wormald, Sam; Wilcox, Stephen; O'Connor, Liam; Dickins, Ross A.; Blewitt, Marnie E.; Ritchie, Matthew E.;
(2014)

Pooled library sequencing screens that perturb gene function in a high-throughput manner are becoming increasingly popular in functional genomics research. Irrespective of the mechanism by which loss of function is achieved, via either RNA interference using short hairp... View more
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