DE-kupl: exhaustive capture of biological variation in RNA-seq data through k-mer decomposition

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Audoux, Jérôme; Philippe, Nicolas; Chikhi, Rayan; Salson, Mikaël; Gallopin, Mélina; Gabriel, Marc; Le Coz, Jérémy; Drouineau, Emilie; Commes, Thérèse; Gautheret, Daniel;

We introduce a k-mer-based computational protocol, DE-kupl, for capturing local RNA variation in a set of RNA-seq libraries, independently of a reference genome or transcriptome. DE-kupl extracts all k-mers with differential abundance directly from the raw data files. T... View more
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