publication . Article . 2018

Morphological Transformation of Peptide Nanoassemblies through Conformational Transition of Core-forming Peptides

Waku, Tomonori; Hirata, Naoyuki; Nozaki, Masamichi; Nogami, Kanta; Kunugi, Shigeru; Tanaka, Naoki;
Open Access
  • Published: 01 Dec 2018 Journal: Polymers, volume 11, page 39 (eissn: 2073-4360, Copyright policy)
  • Publisher: MDPI AG
Abstract
<jats:p>Morphological control of nanostructures that are composed of amphiphilic di- or tri-block molecules by external stimuli broadens their applications for molecular containers, nanoreactors, and controlled release materials. In this study, triblock amphiphiles comprising oligo(ethylene glycol), oligo(l-lysine), and tetra(l-phenylalanine) were prepared for the construction of nanostructures that can transform accompanying α-to-β transition of core-forming peptides. Circular dichroic (CD) measurements showed that the triblock amphiphiles adopted different secondary structures depending on the solvent environment: they adopt β-sheet structures in aqueous solut...
Subjects
free text keywords: Aqueous solution, Organic chemistry, Self-assembly, Amphiphile, Vesicle, Nanoreactor, Chemical engineering, Ethylene glycol, chemistry.chemical_compound, chemistry, Nanostructure, Materials science, Nanomaterials, Communication, aromatic peptides, morphological change, secondary structure
31 references, page 1 of 3

Förster, S., Antonietti, M.. Amphiphilic block copolymers in structure-controlled nanomaterial hybrids. Adv. Mater.. 1998; 10: 195-217 [DOI]

Li, M.H., Keller, P.. Stimuli-responsive polymer vesicles. Soft Matter. 2009; 5: 927-937 [OpenAIRE] [DOI]

Randolph, L.M., Chien, M.P., Gianneschi, N.C.. Biological stimuli and biomolecules in the assembly and manipulation of nanoscale polymeric particles. Chem. Sci.. 2012; 3: 1363-1380 [OpenAIRE] [PubMed] [DOI]

Fuks, G., Talom, R.M., Gauffre, F.. Biohybrid block copolymers: Towards functional micelles and vesicles. Chem. Soc. Rev.. 2011; 40: 2475-2493 [OpenAIRE] [PubMed] [DOI]

Tian, B., Tao, X., Ren, T., Weng, Y., Lin, X., Zhang, Y., Tang, X.. Polypeptide-based vesicles: Formation, properties and application for drug delivery. J. Mater. Chem.. 2012; 22: 17404-17414 [OpenAIRE] [DOI]

Carlsen, A., Lecommandoux, S.. Self-assembly of polypeptide-based block copolymer amphiphiles. Curr. Opin. Colloid Interface Sci.. 2009; 14: 329-339 [OpenAIRE] [DOI]

Cai, C., Wang, L., Lin, J.. Self-assembly of polypeptide-based copolymers into diverse aggregates. Chem. Commun.. 2011; 47: 11189-11203 [OpenAIRE] [DOI]

Hamley, I.W.. PEG–peptide conjugates. Biomacromolecules. 2014; 15: 1543-1559 [OpenAIRE] [PubMed] [DOI]

Orts Gil, G., Łosik, M., Schlaad, H., Drechsler, M., Hellweg, T.. Properties of pH-responsive mixed aggregates of polystyrene-block-poly(L-lysine) and nonionic surfactant in solution and adsorbed at a solid surface. Langmuir. 2008; 24: 12823-12828 [OpenAIRE] [PubMed] [DOI]

Chécot, F., Rodriguez-Hernandez, J., Gnanou, Y., Lecommandoux, S.. pH-responsive micelles and vesicles nanocapsules based on polypeptide diblock copolymers. Biomol. Eng.. 2007; 24: 81-85 [OpenAIRE] [PubMed] [DOI]

Iatrou, H., Frielinghaus, H., Hanski, S., Ferderigos, N., Ruokolainen, J., Ikkala, O., Richter, D., Mays, J., Hadjichristidis, N.. Architecturally induced multiresponsive vesicles from well-defined polypeptides. Formation of gene vehicles. Biomacromolecules. 2007; 8: 2173-2181 [OpenAIRE] [PubMed] [DOI]

Chécot, F., Lecommandoux, S., Gnanou, Y., Klok, H.A.. Water-soluble stimuli-responsive vesicles from peptide-based diblock copolymers. Angew. Chem. Int. Ed.. 2002; 41: 1339-1343 [OpenAIRE] [DOI]

Kukula, H., Schlaad, H., Antonietti, M., Förster, S.. The formation of polymer vesicles or “peptosomes” by polybutadiene-block-poly(L-glutamate) s in dilute aqueous solution. J. Am. Chem. Soc.. 2002; 124: 1658-1663 [OpenAIRE] [PubMed] [DOI]

Bellomo, E.G., Wyrsta, M.D., Pakstis, L., Pochan, D.J., Deming, T.J.. Stimuli-responsive polypeptide vesicles by conformation-specific assembly. Nat. Mater.. 2004; 3: 244-248 [OpenAIRE] [PubMed] [DOI]

Kühnle, R.I., Börner, H.G.. Calcium ions to remotely control the reversible switching of secondary and quaternary structures in bioconjugates. Angew. Chem. Int. Ed.. 2011; 50: 4499-4502 [OpenAIRE] [PubMed] [DOI]

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publication . Article . 2018

Morphological Transformation of Peptide Nanoassemblies through Conformational Transition of Core-forming Peptides

Waku, Tomonori; Hirata, Naoyuki; Nozaki, Masamichi; Nogami, Kanta; Kunugi, Shigeru; Tanaka, Naoki;