Activation of β-Globin Promoter by Erythroid Krüppel-Like Factor

Other literature type English OPEN
Asano, Haruhiko; Stamatoyannopoulos, George;
  • Publisher: American Society for Microbiology
  • Identifiers: pmc: PMC121459
  • Subject: Transcriptional Regulation

Erythroid Krüppel-like factor (EKLF), an erythroid tissue-specific Krüppel-type zinc finger protein, binds to the β-globin gene CACCC box and is essential for β-globin gene expression. EKLF does not activate the γ gene, the CACCC sequence of which differs from that of t... View more
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