Theranostic Approach for Metastatic Pigmented Melanoma Using ICF15002, a Multimodal Radiotracer for Both PET Imaging and Targeted Radionuclide Therapy1

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Rbah-Vidal, Latifa ; Vidal, Aurélien ; Billaud, Emilie M.F. ; Besse, Sophie ; Ranchon-Cole, Isabelle ; Mishellany, Florence ; Perrot, Yann ; Maigne, Lydia ; Moins, Nicole ; Guerquin-Kern, Jean-Luc ; Degoul, Françoise ; Chezal, Jean-Michel ; Auzeloux, Philippe ; Miot-Noirault, Elisabeth (2016)
  • Publisher: Neoplasia Press
  • Journal: Neoplasia (New York, N.Y.), volume 19, issue 1, pages 17-27 (issn: 1522-8002, eissn: 1476-5586)
  • Related identifiers: doi: 10.1016/j.neo.2016.11.001, pmc: PMC5157796
  • Subject: Original article

PURPOSE: This work reports, in melanoma models, the theranostic potential of ICF15002 as a single fluorinated and iodinated melanin-targeting compound. METHODS: Studies were conducted in the murine syngeneic B16BL6 model and in the A375 and SK-MEL-3 human xenografts. IC... View more
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