The sustained release of basic fibroblast growth factor accelerates angiogenesis and the engraftment of the inactivated dermis by high hydrostatic pressure

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Le, Tien Minh; Morimoto, Naoki; Mitsui, Toshihito; Notodihardjo, Sharon Claudia; Munisso, Maria Chiara; Kakudo, Natsuko; Kusumoto, Kenji;
(2019)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE, volume 14, issue 2 ( eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0208658, pmc: PMC6383993
  • Subject: Research Article | Medicine and Health Sciences | Surgical and Invasive Medical Procedures | Plastic Surgery and Reconstructive Techniques | Skin Grafting | Biology and Life Sciences | Anatomy | Integumentary System | Skin | Dermis | Medicine and Health Sciences | Anatomy | Integumentary System | Skin | Dermis | Biology and Life Sciences | Cell Biology | Cellular Types | Animal Cells | Connective Tissue Cells | Fibroblasts | Biology and Life Sciences | Anatomy | Biological Tissue | Connective Tissue | Connective Tissue Cells | Fibroblasts | Medicine and Health Sciences | Anatomy | Biological Tissue | Connective Tissue | Connective Tissue Cells | Fibroblasts | Biology and Life Sciences | Bioengineering | Biotechnology | Medical Devices and Equipment | Medical Implants | Engineering and Technology | Bioengineering | Biotechnology | Medical Devices and Equipment | Medical Implants | Medicine and Health Sciences | Medical Devices and Equipment | Medical Implants | Biology and Life Sciences | Physiology | Cardiovascular Physiology | Angiogenesis | Medicine and Health Sciences | Physiology | Cardiovascular Physiology | Angiogenesis | Biology and Life Sciences | Developmental Biology | Angiogenesis | Medicine and Health Sciences | Endocrinology | Endocrine Physiology | Growth Factors | Biology and Life Sciences | Physiology | Endocrine Physiology | Growth Factors | Medicine and Health Sciences | Physiology | Endocrine Physiology | Growth Factors | Biology and Life Sciences | Anatomy | Histology | Medicine and Health Sciences | Anatomy | Histology | Biology and Life Sciences | Anatomy | Integumentary System | Skin | Epidermis | Medicine and Health Sciences | Anatomy | Integumentary System | Skin | Epidermis

We developed a novel skin regeneration therapy combining nevus tissue inactivated by high hydrostatic pressure (HHP) in the reconstruction of the dermis with a cultured epidermal autograft (CEA). The issue with this treatment is the unstable survival of CEA on the inact... View more
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