FastTree: Computing Large Minimum Evolution Trees with Profiles instead of a Distance Matrix

Article English OPEN
Price, Morgan N.; Dehal, Paramvir S.; Arkin, Adam P.;
  • Publisher: Oxford University Press
  • Journal: Molecular Biology and Evolution,volume 26,issue 7,pages1,641-1,650 (issn: 0737-4038, eissn: 1537-1719)
  • Related identifiers: pmc: PMC2693737, doi: 10.1093/molbev/msp077
  • Subject: Neighbor-Joining | minimum evolution | Research Articles | large phylogenies

Gene families are growing rapidly, but standard methods for inferring phylogenies do not scale to alignments with over 10,000 sequences. We present FastTree, a method for constructing large phylogenies and for estimating their reliability. Instead of storing a distance ... View more
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