publication . Other literature type . 2015

STAT4 rs7574865 polymorphism contributes to the risk of type 1 diabetes: a meta analysis

Li, Chaolin; Zhao, Lujie; Wang, Wei; Li, Huafeng; Meng, Xiaomei; Chen, Shulin;
Open Access English
  • Published: 15 Feb 2015
  • Publisher: e-Century Publishing Corporation
Abstract
The signal transducer and activator of transcription 4 (STAT4) rs7574865 polymorphism has been indicated to be correlated with type 1 diabetes (T1D) susceptibility, but study results are still debatable. Thus, a meta-analysis was conducted. The electronic databases PubMed, Embase, CNKI, and Web of Science (ISI) were searched to find eligible studies. Data were extracted and pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated. A significant association was found between STAT4 rs7574865 polymorphism and T1D risk (OR=1.30; 95% CI, 1.13-1.48; P<0.01; I2=73%). Significant associations were also found in Asians (OR=1.33; 95% CI, 1.04-1.71; P=0.0...
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Other literature type . 2015
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