Quiet Time: Gene Program Prevents Division but Keeps Cells at the Ready
Coller, Hilary A
Roberts, James M
- Publisher: Public Library of Science
(issn: 1544-9173, eissn: 1545-7885)
Research Article | Cell Biology | In Vitro
Cellular quiescence, defined as reversible growth/proliferation arrest, is thought to represent a homogenous state induced by diverse anti-mitogenic signals. We used transcriptional profiling to characterize human diploid fibroblasts that exited the cell cycle after exp...