Structural Basis for the Growth Factor Activity of Human Adenosine Deaminase ADA2*♦

Other literature type English OPEN
Zavialov, Anton V.; Yu, Xiaodi; Spillmann, Dorothe; Lauvau, Grégoire; Zavialov, Andrey V.;

Two distinct adenosine deaminases, ADA1 and ADA2, are found in humans. ADA1 has an important role in lymphocyte function and inherited mutations in ADA1 result in severe combined immunodeficiency. The recently isolated ADA2 belongs to the novel family of adenosine deami... View more
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