publication . Other literature type . Article . 2012

Plasticity of cortical inhibition in dystonia

Meunier, Sabine; Russmann, Heike; Shamim, Ejaz; Lamy, Jean-Charles; Hallett, Mark;
Open Access English
  • Published: 01 Mar 2012
Abstract
Artificial induction of plasticity by paired associative stimulation (PAS) in healthy volunteers (HV) demonstrates Hebbian-like plasticity in selected inhibitory networks as well as excitatory networks. In a group of 17 patients with focal hand dystonia and a group of 19 HV, we evaluated how PAS and the learning of a simple motor task influence the circuits supporting long-interval intracortical inhibition (LICI, reflecting activity of GABAB interneurons) and long-latency afferent inhibition (LAI, reflecting activity of somatosensory inputs to the motor cortex). In HV, PAS and motor learning induced long-term potentiation (LTP)-like plasticity of excitatory netw...
Subjects
free text keywords: Article, General Neuroscience, Synaptic plasticity, Excitatory postsynaptic potential, Neuroscience, Transcranial magnetic stimulation, medicine.medical_treatment, medicine, Motor learning, Motor cortex, medicine.anatomical_structure, Biology, Somatosensory system, Long-term potentiation, Neuroplasticity
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publication . Other literature type . Article . 2012

Plasticity of cortical inhibition in dystonia

Meunier, Sabine; Russmann, Heike; Shamim, Ejaz; Lamy, Jean-Charles; Hallett, Mark;