Impaired reductive regeneration of ascorbic acid in the Goto-Kakizaki diabetic rat.

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Kashiba, M; Oka, J; Ichikawa, R; Kageyama, A; Inayama, T; Kageyama, H; Ishikawa, T; Nishikimi, M; Inoue, M; Inoue, S;

Ascorbic acid (AA) is a naturally occurring major antioxidant that is essential for the scavenging of toxic free radicals in both plasma and tissues. AA levels in plasma and tissues have been reported to be significantly lower than normal in diabetic animals and humans,... View more
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