publication . Article . Other literature type . 2008

Microparticle surface protein are associated with experimental venous thrombosis: a preliminary study.

Abdullah, N. M.; Kachman, M.; Walker, A.; Hawley, A. E.; Wrobleski, S. K.; Myers, D. D.; Strahler, J. R.; Philip Andrews; Michailidis, G. C.; Ramacciotti, E.; ...
Open Access
  • Published: 21 Nov 2008 Journal: Clinical and Applied Thrombosis/Hemostasis (issn: 1076-0296, Copyright policy)
  • Publisher: SAGE Publications
Abstract
Microparticles (MPs) are small membrane vesicles released from activated cells and are associated with thrombosis and inflammation. Microparticles contain a unique subset of surface proteins derived from the parent cell and may be responsible for their diverse biological functions. To identify these proteins juvenile baboons (Papio anubis, n=4) underwent iliac vein thrombosis with six-hour balloon occlusion. Plasma samples were taken at baseline and at 2 days post thrombosis for MP analysis. Microparticles were extracted from platelet-poor plasma, digested separately with trypsin and tagged using iTRAQ reagents. The digests were subjected to 2-D LC separation fo...
Subjects
free text keywords: Hematology, General Medicine, Diabetes mellitus, medicine.disease, medicine, Internal medicine, medicine.medical_specialty, Microparticle, Venous thrombosis, Cardiology, business.industry, business, Article
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publication . Article . Other literature type . 2008

Microparticle surface protein are associated with experimental venous thrombosis: a preliminary study.

Abdullah, N. M.; Kachman, M.; Walker, A.; Hawley, A. E.; Wrobleski, S. K.; Myers, D. D.; Strahler, J. R.; Philip Andrews; Michailidis, G. C.; Ramacciotti, E.; ...