publication . Article . 2018

Role of MicroRNAs Induced by Chinese Herbal Medicines Against Hepatocellular Carcinoma: A Brief Review.

Ge Guo; Juhua Zhou; Xiaogaung Yang; Jiang Feng; Yanxia Shao; Tingting Jia; Qingrong Huang; Yanmin Li; Yin Zhong; Prakash S. Nagarkatti; ...
Open Access English
  • Published: 01 Oct 2018 Journal: Integrative Cancer Therapies, volume 17, issue 4, pages 1,059-1,067 (issn: 1534-7354, eissn: 1552-695X, Copyright policy)
  • Publisher: SAGE Publications
Abstract
MicroRNAs (miRNAs) are highly conserved, noncoding small RNAs that regulate gene expression, and consequently several important functions including early embryo development, cell cycle, programmed cell death, cell differentiation, and metabolism. While there are no effective treatments available against hepatocellular carcinoma (HCC), some Chinese herbal medicines have been shown to regulate growth, differentiation, invasion, and metastasis of HCC. Many studies have shown that Chinese herbal medicines regulate the expression of miRNAs and this may be associated with their ability to control the development of HCC. In this article, the effects of Chinese herbal m...
Subjects
Medical Subject Headings: digestive system diseases
free text keywords: Review Articles, miRNAs, Chinese herbal medicines, hepatocellular carcinoma, Gene expression, Cancer research, Cellular differentiation, medicine.disease, medicine, Cell cycle, Metastasis, business.industry, business, Biomarker (medicine), microRNA, Physical therapy, medicine.medical_specialty, Programmed cell death
76 references, page 1 of 6

1 Altekruse SF Henley SJ Cucinelli JE McGlynn KA.Changing hepatocellular carcinoma incidence and liver cancer mortality rates in the United States. Am J Gastroenterol. 2014;109:542-553.24513805 [OpenAIRE] [PubMed]

2 Ting CT Kuo CJ Hu HY Lee YL Tsai TH.Prescription frequency and patterns of Chinese herbal medicine for liver cancer patients in Taiwan: a cross-sectional analysis of the National Health Insurance Research Database. BMC Complement Altern Med. 2017;17:118.28219357 [OpenAIRE] [PubMed]

3 Chen W Zheng R Baade PD et al Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66:115-132.26808342 [PubMed]

4 Torre LA Siegel RL Ward EM Jemal A.Global cancer incidence and mortality rates and trends—an update. Cancer Epidemiol Biomarkers Prev. 2016;25:16-27.26667886 [PubMed]

5 Maucort-Boulch D de Martel C Franceschi S Plummer M.Fraction and incidence of liver cancer attributable to hepatitis B and C viruses worldwide. Int J Cancer. 2018;142:2471-2477.29388206 [OpenAIRE] [PubMed]

6 Marengo A Rosso C Bugianesi E.Liver cancer: connections with obesity, fatty liver, and cirrhosis. Annu Rev Med. 2016;67:103-117.26473416 [OpenAIRE] [PubMed]

7 Marquardt JU Andersen JB Thorgeirsson SS.Functional and genetic deconstruction of the cellular origin in liver cancer. Nat Rev Cancer. 2015;15:653-667.26493646 [OpenAIRE] [PubMed]

8 Callegari E Gramantieri L Domenicali M D’Abundo L Sabbioni S Negrini M.MicroRNAs in liver cancer: a model for investigating pathogenesis and novel therapeutic approaches. Cell Death Differ. 2015;22:46-57.25190143 [OpenAIRE] [PubMed]

9 Bruix J Qin S Merle P et al; RESORCE Investigators. Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2017;389:56-66.27932229 [OpenAIRE] [PubMed]

10 Kim VN Nam JW.Genomics of microRNA. Trends Genet. 2006;22:165-173.16446010 [PubMed]

11 Pal AS Kasinski AL.Animal models to study microRNA function. Adv Cancer Res. 2017;135:53-118.28882225 [OpenAIRE] [PubMed]

12 Carthew RW Agbu P Giri R.MicroRNA function in Drosophila melanogaster. Semin Cell Dev Biol. 2017;65:29-37.27000418 [OpenAIRE] [PubMed]

13 Bao L Yan Y Xu C et al MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways. Cancer Lett. 2013;337:226-236.23684551 [PubMed]

14 Wang N Tan HY Chan YT Guo W Li S Feng Y.Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde. Oncotarget. 2017;8:105848-105859.29285297 [OpenAIRE] [PubMed]

15 Huang Z Huang Q Ji L et al Epigenetic regulation of active Chinese herbal components for cancer prevention and treatment: a follow-up review. Pharmacol Res. 2016;114:1-12.27697644 [PubMed]

76 references, page 1 of 6
Abstract
MicroRNAs (miRNAs) are highly conserved, noncoding small RNAs that regulate gene expression, and consequently several important functions including early embryo development, cell cycle, programmed cell death, cell differentiation, and metabolism. While there are no effective treatments available against hepatocellular carcinoma (HCC), some Chinese herbal medicines have been shown to regulate growth, differentiation, invasion, and metastasis of HCC. Many studies have shown that Chinese herbal medicines regulate the expression of miRNAs and this may be associated with their ability to control the development of HCC. In this article, the effects of Chinese herbal m...
Subjects
Medical Subject Headings: digestive system diseases
free text keywords: Review Articles, miRNAs, Chinese herbal medicines, hepatocellular carcinoma, Gene expression, Cancer research, Cellular differentiation, medicine.disease, medicine, Cell cycle, Metastasis, business.industry, business, Biomarker (medicine), microRNA, Physical therapy, medicine.medical_specialty, Programmed cell death
76 references, page 1 of 6

1 Altekruse SF Henley SJ Cucinelli JE McGlynn KA.Changing hepatocellular carcinoma incidence and liver cancer mortality rates in the United States. Am J Gastroenterol. 2014;109:542-553.24513805 [OpenAIRE] [PubMed]

2 Ting CT Kuo CJ Hu HY Lee YL Tsai TH.Prescription frequency and patterns of Chinese herbal medicine for liver cancer patients in Taiwan: a cross-sectional analysis of the National Health Insurance Research Database. BMC Complement Altern Med. 2017;17:118.28219357 [OpenAIRE] [PubMed]

3 Chen W Zheng R Baade PD et al Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66:115-132.26808342 [PubMed]

4 Torre LA Siegel RL Ward EM Jemal A.Global cancer incidence and mortality rates and trends—an update. Cancer Epidemiol Biomarkers Prev. 2016;25:16-27.26667886 [PubMed]

5 Maucort-Boulch D de Martel C Franceschi S Plummer M.Fraction and incidence of liver cancer attributable to hepatitis B and C viruses worldwide. Int J Cancer. 2018;142:2471-2477.29388206 [OpenAIRE] [PubMed]

6 Marengo A Rosso C Bugianesi E.Liver cancer: connections with obesity, fatty liver, and cirrhosis. Annu Rev Med. 2016;67:103-117.26473416 [OpenAIRE] [PubMed]

7 Marquardt JU Andersen JB Thorgeirsson SS.Functional and genetic deconstruction of the cellular origin in liver cancer. Nat Rev Cancer. 2015;15:653-667.26493646 [OpenAIRE] [PubMed]

8 Callegari E Gramantieri L Domenicali M D’Abundo L Sabbioni S Negrini M.MicroRNAs in liver cancer: a model for investigating pathogenesis and novel therapeutic approaches. Cell Death Differ. 2015;22:46-57.25190143 [OpenAIRE] [PubMed]

9 Bruix J Qin S Merle P et al; RESORCE Investigators. Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2017;389:56-66.27932229 [OpenAIRE] [PubMed]

10 Kim VN Nam JW.Genomics of microRNA. Trends Genet. 2006;22:165-173.16446010 [PubMed]

11 Pal AS Kasinski AL.Animal models to study microRNA function. Adv Cancer Res. 2017;135:53-118.28882225 [OpenAIRE] [PubMed]

12 Carthew RW Agbu P Giri R.MicroRNA function in Drosophila melanogaster. Semin Cell Dev Biol. 2017;65:29-37.27000418 [OpenAIRE] [PubMed]

13 Bao L Yan Y Xu C et al MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways. Cancer Lett. 2013;337:226-236.23684551 [PubMed]

14 Wang N Tan HY Chan YT Guo W Li S Feng Y.Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde. Oncotarget. 2017;8:105848-105859.29285297 [OpenAIRE] [PubMed]

15 Huang Z Huang Q Ji L et al Epigenetic regulation of active Chinese herbal components for cancer prevention and treatment: a follow-up review. Pharmacol Res. 2016;114:1-12.27697644 [PubMed]

76 references, page 1 of 6
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publication . Article . 2018

Role of MicroRNAs Induced by Chinese Herbal Medicines Against Hepatocellular Carcinoma: A Brief Review.

Ge Guo; Juhua Zhou; Xiaogaung Yang; Jiang Feng; Yanxia Shao; Tingting Jia; Qingrong Huang; Yanmin Li; Yin Zhong; Prakash S. Nagarkatti; ...