Mitogen-activated protein kinase mediates mevalonate-stimulated human mesangial cell proliferation

Article English OPEN
ZHOU, XIAOSHUANG; WANG, CHEN; TIAN, JIHUA; WANG, YANHONG; LI, YAFENG; HU, ZHAOYONG; LI, RONGSHAN;
(2015)
  • Publisher: D.A. Spandidos
  • Journal: Molecular Medicine Reports,volume 12,issue 2,pages2,643-2,649 (issn: 1791-2997, eissn: 1791-3004)
  • Related identifiers: doi: 10.3892/mmr.2015.3715, pmc: PMC4464046
  • Subject: 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor | apoptosis | mesangial cell | Articles | mevalonate

The metabolic products of intracellular mevalonate (MVA) are important for the growth of eukaryotic cells. These products include cholesterol and several non-sterol isoprenoids. It has been reported that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors amelior... View more
Share - Bookmark