Mitogen-activated protein kinase mediates mevalonate-stimulated human mesangial cell proliferation

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ZHOU, XIAOSHUANG ; WANG, CHEN ; TIAN, JIHUA ; WANG, YANHONG ; LI, YAFENG ; HU, ZHAOYONG ; LI, RONGSHAN (2015)
  • Publisher: D.A. Spandidos
  • Journal: Molecular Medicine Reports, volume 12, issue 2, pages 2,643-2,649 (issn: 1791-2997, eissn: 1791-3004)
  • Related identifiers: doi: 10.3892/mmr.2015.3715, pmc: PMC4464046
  • Subject: 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor | apoptosis | mesangial cell | Articles | mevalonate

The metabolic products of intracellular mevalonate (MVA) are important for the growth of eukaryotic cells. These products include cholesterol and several non-sterol isoprenoids. It has been reported that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors amelior... View more
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