Inhibition of nasopharyngeal carcinoma cell proliferation and synergism of cisplatin with silvestrol and episilvestrol isolated from Aglaia stellatopilosa

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DAKER, MAELINDA; YEO, JIUN-TZEN; BAKAR, NORHASIMAH; ABDUL RAHMAN, ASMA' SAIYIDATINA AISHAH ABDUL; AHMAD, MUNIRAH; YEO, TIONG-CHIA; KHOO, ALAN SOO-BENG;
(2016)
  • Publisher: D.A. Spandidos
  • Journal: Experimental and Therapeutic Medicine,volume 11,issue 6,pages2,117-2,126 (issn: 1792-0981, eissn: 1792-1015)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.3892/etm.2016.3201, pmc: PMC4887938
  • Subject: nasopharyngeal carcinoma | cell proliferation | Aglaia stellatopilosa | synergism | silvestrol | cell cycle arrest | cisplatin | Articles | episilvestrol
    mesheuropmc: otorhinolaryngologic diseases | stomatognathic diseases

Nasopharyngeal carcinoma (NPC) is a type of tumour that arises from the epithelial cells that line the surface of the nasopharynx. NPC is treated with radiotherapy and cytotoxic chemotherapeutic drugs such as cisplatin and 5-fluorouracil. However, current strategies are... View more
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