Evaluation of MAGE-1 and MAGE-3 as tumour-specific markers to detect blood dissemination of hepatocellular carcinoma cells

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Mou, D-C; Cai, S-L; Peng, J-R; Wang, Y; Chen, H-S; Pang, X-W; Leng, X-S; Chen, W-F;
  • Publisher: Nature Publishing Group
  • Journal: British Journal of Cancer,volume 86,issue 1,pages110-116 (issn: 0007-0920, eissn: 1532-1827)
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  • Related identifiers: doi: 10.1038/sj.bjc.6600016, pmc: PMC2746529
  • Subject: Molecular and Cellular Pathology | MAGE transcripts | circulating tumour cells | nested polymerase chain reaction | tumour-specific marker | hepatocellular carcinoma
    mesheuropmc: endocrine system | neoplasms

The members of MAGE gene family are highly expressed in human hepatocellular carcinoma (HCC). In the present study, we tested the tumour-specific MAGE-1 and MAGE-3 transcripts in the peripheral blood of HCC patients by nested RT–PCR to detect the circulating tumour cell... View more
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