FKLF, a Novel Krüppel-Like Factor That Activates Human Embryonic and Fetal β-Like Globin Genes

Other literature type English OPEN
Asano, Haruhiko; Li, Xi Susan; Stamatoyannopoulos, George;
  • Publisher: American Society for Microbiology
  • Identifiers: pmc: PMC84149
  • Subject: Cell Growth and Development

A cDNA encoding a novel Krüppel-type zinc finger protein, FKLF, was cloned from fetal globin-expressing human fetal erythroid cells. The deduced polypeptide sequence composed of 512 amino acids revealed that, like Sp1 and EKLF, FKLF has three contiguous zinc fingers at ... View more
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