Drastic Reduction in the Production of Subviral Particles Does Not Impair Hepatitis B Virus Virion Secretion▿ †

Other literature type English OPEN
Garcia, Tamako; Li, Jisu; Sureau, Camille; Ito, Kiyoaki; Qin, Yanli; Wands, Jack; Tong, Shuping;
  • Publisher: American Society for Microbiology (ASM)
  • Related identifiers: pmc: PMC2772768, doi: 10.1128/JVI.00905-09
  • Subject: Genome Replication and Regulation of Viral Gene Expression
    mesheuropmc: viruses

Hepatitis B virus (HBV) contains three coterminal envelope proteins on the virion surface: large (L), middle (M), and small (S). The M and S proteins are also secreted as empty “subviral particles,” which exceed virions by at least 1,000-fold. The S protein serves as th... View more
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