publication . Article . 2007

Comparison of bronchial responsiveness to ultrasonically nebulized distilled water (UNDW), methacholine, and ultrasonically nebulized distilled cold water (UDCW) in patients with sulfur mustard gas-induced asthma

Ali Emad; Yasaman Emad;
Open Access English
  • Published: 01 Jun 2007 Journal: Clinical Toxicology (Philadelphia, Pa.), volume 45, issue 5, pages 565-570 (issn: 1556-3650, eissn: 1556-9519, Copyright policy)
  • Publisher: Informa Healthcare
Abstract
Objective To evaluate bronchial challenges using three different stimuli as screening tools for bronchial hyper-responsiveness in sulfur mustard gas-induced asthma. Design Randomized, cross-over clinical study. Setting University hospital. Patients Eighteen veterans with mustard gas-induced asthma and 18 normal veterans as the control group. Intervention Pulmonary function tests and inhalation challenges with ultrasonically nebulized distilled water (UNDW), methacholine, and ultrasonically nebulized cold water (UNDCW) were performed on all patients and subjects. Results Six mustard gas-induced asthmatic veterans did not respond to a 20% in FEV1 after distilled w...
Subjects
Medical Subject Headings: respiratory tract diseases
free text keywords: Article, Musta Mustard, Asthma, Metacholine, Provocation, Toxicology, General Medicine, Inhalation, Sulfur Mustard Gas, Methacholine, medicine.drug, medicine, Anesthesia, Provocation test, business.industry, business, Pulmonary function testing, Sulfur mustard, chemistry.chemical_compound, chemistry, Distilled water, medicine.disease
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29 references, page 1 of 2

Reports of specialists appointed by the Secretary General to investigate allegations by the Islamic Republic of Iran concerning the use of chemical weapons. 1986

Emad, A, Rezaian, GR. The diversity of the effects of sulfur mustard gas inhalation on respiratory system 10 years after a single, heavy exposure: Analysis of 197 cases. Chest. 1997; 112: 734-8 [PubMed]

Wormser, U. Toxicology of mustard gas. Trends Pharmacol Sci. 1991; 12: 164-7 [PubMed]

Calvet, JH, Jarreau, PH, Levame, M, Ortho, MP, Lorino, H, Harf, A, Macquin-Mavier, I. Acute and chronic respiratory effects of sulfur mustard intoxication in guinea pig. J Appl Physiol. 1994; 76: 681-8 [OpenAIRE] [PubMed]

Chevillard, M, Lainee, P, Robineau, P, Puchelle, E. Toxic effects of sulfur mustard on respiratory epithelial cells in culture. Cell Biol Toxicol. 1992; 8: 171-81 [OpenAIRE] [PubMed]

Willems, JL. Clinical management of mustard gas casualties. Ann Med Milit Belg. 1959; 3: S1-S61

Emad, A, Rezaian, GR. Characteristics of bronchoalveolar lavage fluid in patients with sulfur mustard gas-induced asthma or chronic bronchitis. Am J Med. 1999; 106: 689-690 [PubMed]

Quackenboss, JJ, Lebowitz, MD, Krzyzanowski, M. The normal range of diurnal changes in peak expiratory flow rates: Relationship to symptoms and respiratory diseases. Am Rev Respir Dis. 1991; 143: 323-30 [PubMed]

Clark, TJ, Hetzel, MR. Diurnal variation of asthma. Br J Dis Chest. 1977; 71: 87-92 [OpenAIRE] [PubMed]

Ries, AK, Clausen, JL. Response to bronchodilators. Pulmonary function testing: Guidelines and controversies. 1982: 215-21

Gardner, R, Kankinson, J, Clausen, J, Crapo, R, Johnson, R. Standardization of spirometry-1987 update. Am Rev Respir Dis. 1987; 136: 1285-98 [PubMed]

Zapletal, A, Samanek, M, Paul, T. Lung function in children and adolescence: Methods, reference values. Progr Respir Res. 1987; 22: 113-218

Lung function testing: Selection of reference values and interpretative strategies. Am Rev Respir Dis. 1991; 144: 1202-1218 [PubMed]

Sterk, PJL, Fabbri, LM, Quarnier, PhH, Cockcroft, DW, O'Byrne, PM, Anderson, SD, Juniper, EF, Malo, JL. Airway responsiveness. Standardized challenge testing with pharmacological, physical and sensitized stimuli in adults. Eur Respir J. 1993; 16 (suppl): 53-58 [OpenAIRE]

Chetta, A, Foresi, A, Donno, MD, Consigli, GF, Bertorelli, G, Pesci, A, Barbee, RA, Olivieri, D. Bronchial responsiveness to distilled water and methacholine and its relationship to inflammation and remodelling of the airways in asthma. Am J Respir Crit Care Med. 1996; 153: 910-917 [PubMed]

29 references, page 1 of 2
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publication . Article . 2007

Comparison of bronchial responsiveness to ultrasonically nebulized distilled water (UNDW), methacholine, and ultrasonically nebulized distilled cold water (UDCW) in patients with sulfur mustard gas-induced asthma

Ali Emad; Yasaman Emad;